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US 10,231,903 B2Granted
Pharmaceutical compounding methods and systems
AssigneeMedisca Pharmaceutique Inc.
InventorsPanagiota Danopoulos, Sarah Nyat Peng Wong, Vargha Talebi, Patrick-Martin Bader, Marc Joiner
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.
Claims27
A compounding method, comprising:
- a) in a pharmacy setting, providing a container including therein a plurality of gelatin gum base pieces;
- b) subjecting the container to first superimposed revolution and rotation movements, wherein the first superimposed revolution and rotation movements are sufficient to melt the plurality of gelatin gum base pieces without addition of external heat, thereby obtaining a pourable liquid composition;
- c) adding an active pharmaceutical ingredient (API) into the pourable liquid composition to obtain an API-containing composition;
- d) subjecting the container comprising the API-containing composition to second superimposed revolution and rotation movements to mix the API-containing composition and obtain a dispersed composition;
- and
- e) cooling the dispersed composition to obtain a solid, semi-solid, or chewable composition.
3 more elements
A compounding method, comprising:
- a) providing a container with a plurality of gelatin gum base pieces therein;
- b) subjecting the container to superimposed revolution and rotation movements, wherein the superimposed revolution and rotation movements are sufficient to melt the plurality of gelatin gum base pieces without addition of external heat, to obtain a pourable liquid composition contained in the container, the pourable liquid composition including melted gelatin gum base pieces;
- and
- c) pouring the liquid composition into a mold having a desired shape and cooling the liquid composition to obtain a solid, semi-solid, or chewable composition in said desired shape.
1 more element
Dependencies are inferred from the claim text.