Increased stiffness center optic in soft contact lenses for astigmatism correction
AssigneeJohnson & Johnson Vision Care, Inc.
InventorsAzaam Alli, Dola Sinha
Life of this patent
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Abstract
A molded contact lens comprising a stiffer optic zone relative to the peripheral zone of the contact lens provides an optical element for correcting astigmatism without the need for or substantially minimizing the need for the correction of rotational misalignment. The higher elastic modulus optic zone vaults over the cornea thereby allowing a tear lens to form. The tear lens follows or assumes the shape of the back surface of the contact lens. The combination of the tear lens and the optical zone provide an optical element for correction of refractive error.
Claims36
An ophthalmic device comprising:
- a contact lens having a central optic zone and a peripheral zone surrounding the central optic zone, the peripheral zone being formed from a second material having a second Young's modulus;
- and
- a first material incorporated into the central optic zone of the contact lens, the first material having a first Young's modulus of at least about 1000 psi and a water content of at least about 10%, formed from a first reactive mixture comprising at least one N-alkyl methacrylamide and at least one silicone-containing component.
The ophthalmic device of any of the foregoing claims wherein said silicone containing component comprises at least one silicone chain having 3-30 siloxane repeating units.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture comprises about 20 to about 60 wt % of said silicone containing component, based upon all reactive components.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture comprises about 5 wt % to about 50 wt % of at least one N-alkyl methacrylamide, based upon all reactive components.
The ophthalmic device of any of the foregoing claims wherein the second material is formed from a reaction mixture containing a silicone-containing component, said silicone-containing component is selected from compounds of Formulae IIIa through IVc, and combinations thereof:
- wherein R1 is a hydrogen atom or methyl;
- Z is selected from O, N, S or NR1CH2CH2O;
- when Z═O or S, R2 is not required;
- wherein j is a whole number between 1 and 20;
- wherein R19 is
- a substituted or unsubstituted C1-6, C1-4 or C2-4 alkylene segment (CH2)r
- each methylene group may optionally be independently substituted with ethers, amines, carbonyls, carboxylates, carbamates and combinations thereof;
- or
- an oxyalkylene segment (OCH2)k and
- k is a whole number from one to three, or wherein R19 may be a mixture of alkylene and oxyalkylene segments and the sum of r and k is between 1 and 9;
- wherein each R3 and R4 are independently a linear, branched, or cyclic alkyl group containing between one and six carbon atoms, a linear, branched, or cyclic alkoxy group containing between one and six carbon atoms, a linear or branched polyethyleneoxyalkyl group, a phenyl group, a benzyl group, a substituted or un-substituted aryl group, a fluoroalkyl group, a partially fluorinated alkyl group, a perfluoroalkyl group, a fluorine atom, or combinations thereof;
- wherein R5 is a substituted or un-substituted linear or branched alkyl group having 1 to eight carbon atoms, or 1 to 4 carbon atoms, or methyl or butyl;
- or an aryl group, any of which may be substituted with one or more fluorine atoms.
The ophthalmic device of any of the foregoing claims wherein said at least one N-alkyl methacrylamide has the formula
- wherein R′ is selected from linear, branched, or cyclic alkyl groups containing one to eight carbon atoms, benzyl or phenyl, any of which may be un-substituted or substituted with additional functional groups such as hydroxyl, amino, and combinations thereof.
The ophthalmic device of any of the foregoing claims wherein said first material has a modulus of about 1000 psi to about 200,000 psi, said first reactive mixture comprises about 5 to about 15 wt % at least one crosslinking component.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture further comprises at least one silicone-containing crosslinker.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture comprises about 4 to about 15 wt % said silicone-containing crosslinker.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture comprises about 20 to about 80 wt % of said silicone containing component, based upon all reactive components.
The ophthalmic device of any of the foregoing claims wherein said first reactive mixture comprises about 5 wt % to about 50 wt % of said at least one N-alkyl methacrylamide, based upon all reactive components.
The ophthalmic device of any of the foregoing claims, wherein the ophthalmic device comprises a toric contact lens.
The ophthalmic device according to any of the foregoing claims, wherein the second material comprises Young's modulus less than about 200 psi or 150 psi.
The contact lens of any of the foregoing claims wherein said central zone is about 9 mm or less in diameter.
The contact lens of any of the foregoing claims wherein said central zone has a diameter of between about 4 and about 7 mm.
A contact lens comprising:
- an optic zone being formed from a first material having a first Young's modulus between about 1,000 psi and about 200,000 psi, said first material formed from a reactive mixture comprising at least one N-alkyl methacrylamide and at least one silicone-containing component;
- and
- a peripheral zone formed from a material having a second Young's modulus less than about 200 psi.
A contact lens comprising:
- an optic zone having a first stiffness, said optic zone being formed from a first material having a first Young's modulus between about 1,000 psi and about 200,000 psi, said first material formed from a reactive mixture comprising at least one N-alkyl methacrylamide and at least one silicone-containing component;
- and
- a peripheral zone having a second stiffness formed from a material having a second Young's modulus less than about 200 psi, the first stiffness being greater than the second stiffness.
Dependencies are inferred from the claim text.