US 10,209,334 B2 · System and method for controlling partial volume effects in magnetic resonance fingerprinting

Abstract

Systems and methods for estimating quantitative parameters of a subject from data acquired using a magnetic resonance imaging (MRI) system. The system includes a computer system configured to control the MRI system to acquire MR fingerprinting (MRF) data representing a plurality of different signal evolutions acquired using different acquisition parameter settings and reconstruct the MRF data into at least one image composed of a plurality of pixels or voxels formed of multiple compartments per pixel or voxel. The computer system is further configured to, on a compartment-by-compartment basis, compare a signal associated with each compartment to an initial dictionary comprising a plurality of signal templates that coarsely sample different acquisition parameters used to acquire the MRF data to determine quantitative parameters for each compartment. The computer system is further configured to generate a quantitative parameter map that indicates the quantitative parameters for each compartment.

Claims21

Dependent claims

A magnetic resonance imaging (MRI) system, comprising:

a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject arranged in the MRI system;
a magnetic gradient system including a plurality of magnetic gradient coils configured to apply at least one magnetic gradient field to the polarizing magnetic field;
a radio frequency (RF) system configured to apply an RF field to the subject and to receive magnetic resonance signals from the subject using a coil array;
a computer system programmed to:
control the gradient system and the RF system to acquire MR fingerprinting (MRF) data representing a plurality of different signal evolutions acquired using different acquisition parameter settings;
reconstruct the MRF data into at least one image composed of a plurality of pixels or voxels formed of multiple compartments per pixel or voxel;
on a compartment-by-compartment basis, compare a signal associated with each compartment to an initial dictionary comprising a plurality of signal templates that coarsely sample different acquisition parameters used to acquire the MRF data to determine quantitative parameters for each compartment;
and
generate a quantitative parameter map that indicates the quantitative parameters for each compartment.

6 more elements

Dependencies are inferred from the claim text.

System and method for controlling partial volume effects in magnetic resonance fingerprinting

Life of this patent

System and method for controlling partial volume effects in magnetic resonance fingerprinting

Life of this patent

Abstract

Claims21