Blood sample analyzing method, blood sample analyzer, and system
AssigneeSysmex Corporation
InventorJunki Hayasaki
Life of this patent
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Abstract
Disclosed is a blood sample analyzing method including preparing a measurement specimen by mixing a blood sample with a measuring reagent of fibrin and a fibrinogen degradation product (FDP); acquiring, based on a time-dependent change in optical information obtained by optically measuring the measurement specimen, first information indicating an FDP concentration and second information indicating a curving degree of a time course curve showing the time-dependent change of the optical information; and determining an enhanced fibrinolytic state of the blood sample or acquiring a value related to a D dimer of the blood sample based on the first information and the second information.
Claims20
A blood sample analyzing method comprising:
- preparing a measurement specimen by mixing a blood sample with a measuring reagent of degradation products of fibrin and fibrinogen (FDP);
- acquiring, based on a time-dependent change in optical information obtained by optically measuring the measurement specimen, first information indicating an FDP concentration and second information indicating a curving degree of a time course curve showing the time-dependent change of the optical information;
- and
- determining an enhanced fibrinolytic state of the blood sample or acquiring an estimated value of a D dimer concentration or a value calculated from a D dimer concentration of the blood sample based on the first information and the second information.
A blood sample analyzer comprising:
- a specimen preparing unit that prepares a measurement specimen by mixing a blood sample with a measuring reagent of degradation products of fibrin and fibrinogen (FDP);
- a detection unit that optically measures the measurement specimen and outputs a detection signal;
- and
- a processing unit that acquires, based on optical information of the measurement specimen obtained from the detection signal, first information indicating an FDP concentration and second information indicating a curving degree of a time course curve showing a time-dependent change of the optical information, and determines an enhanced fibrinolytic state of the blood sample or acquires an estimated value of a D dimer concentration or a value calculated from a D dimer concentration of the blood sample based on the first information and the second information.
A system configured to perform a sample analyzing process, comprising:
- a processor, and
- a memory, under control of the processor, including software instructions for executing the sample analyzing process, wherein the processor is configured to execute the software instructions by performing:
- a first process of acquiring, based on a time-dependent change of optical information obtained by optically measuring a measurement specimen that is a mixture of a measuring reagent of degradation products of fibrin and fibrinogen (FDP) and a blood sample, first information indicating an FDP concentration and second information indicating a curving degree of a time course curve showing the time-dependent change of the optical information;
- and
- a second process of determining an enhanced fibrinolytic state of the blood sample based on the first information and the second information.
Dependencies are inferred from the claim text.