Fluorescence histo-tomography (FHT) systems and methods
AssigneeEmit Imaging, Inc.
InventorsJohn W. Hoppin, John V. Frangioni, Robert William Holt, Mohammed Q. Qutaish, Marc Edward Seaman, Mark W. Bordo, Jacob Yost Hesterman
Life of this patent
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Abstract
In one embodiment, a fluorescence histo-tomography (FHT) system is disclosed. The FHT system includes a housing, a fluorescence camera located within the housing, a white light camera located within the housing, and a fluorescence light source located within the housing. The FHT system further includes a support mount configured to support the housing within a chamber of a slicing apparatus such that the cameras and fluorescence light source are aimed towards a block face of a tissue specimen retained within the chamber.
Claims18
A fluorescence histo-tomography (FHT) system comprising:
- a housing;
- a fluorescence camera located within the housing;
- a white light camera located within the housing;
- a fluorescence light source located within the housing;
- and
- a support mount configured to support the housing within a chamber of a slicing apparatus such that the cameras and fluorescence light source are aimed towards a block face of a tissue specimen retained within the chamber, wherein the support mount is removably positionable on a floor of the chamber.
A method of performing fluorescence histo-tomography (FHT) comprising:
- capturing, by an imaging device mounted within a chamber of a slicing apparatus, a white light image of a block face of a tissue specimen retained within the chamber, wherein the imaging device is mounted within the chamber using a support mount in contact with a floor of the chamber;
- capturing, by the imaging device, a fluorescence image of the block face under white light and fluorescence illumination;
- co-registering, by the imaging device, the white light and fluorescence images to form a combined image;
- and
- providing, by the imaging device, the combined image to an electronic display.
A fluorescence histo-tomography (FHT) system comprising:
- a portable housing having a handle to allow a user to removably position the housing within a chamber of a slicing apparatus;
- a fluorescence camera located within the housing;
- a white light camera located within the housing;
- a fluorescence light source located within the housing;
- and
- a support mount configured to support the housing within the chamber such that the cameras and fluorescence light source are aimed towards a block face of a tissue specimen retained within the chamber.
Dependencies are inferred from the claim text.