Cell analyzer system, cell analyzer program, and cell analyzing method
AssigneeSony Corporation
InventorsKazuhiro Nakagawa, Shiori Oshima, Eriko Matsui
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Abstract
A cell analyzer system according to the present technology includes an image acquisition unit, a vibration information extraction unit, and a vibration characteristics calculation unit. The image acquisition unit acquires a cell image by capturing cells at elapsed time. The vibration information extraction unit extracts vibration information attributable to spontaneous membrane potential vibration of cells from the cell image. The vibration characteristics calculation unit calculates vibration characteristics of the vibration information from the vibration information.
Claims15
A cell analyzer system, comprising:
- circuitry configured to:
- acquire a plurality of cell images by capturing a cell over an elapsed time;
- determine a spontaneous membrane potential vibration of the cell, wherein:
- determining the spontaneous membrane potential vibration comprises extracting, from the plurality of cell images, a variation in fluorescence intensity;
- and
- the spontaneous membrane potential vibration indicates a change in membrane potential and the change in membrane potential indicates a change in an electrical potential of the cell membrane;
- and
- determine a status of the cell based at least in part on the spontaneous membrane potential vibration.
At least one non-transitory computer-readable storage medium having encoded thereon a cell analysis program that, when executed by at least one processor of an information processing apparatus, causes the information processing apparatus to carry out a method comprising:
- acquiring a plurality of cell images by capturing a cell over an elapsed time;
- determining a spontaneous membrane potential vibration of the cell, wherein:
- determining the spontaneous membrane potential vibration comprises extracting, from the plurality of cell images, a variation in fluorescence intensity and a movement of the cell;
- and
- the spontaneous membrane potential vibration indicates a change in membrane potential and the change in membrane potential indicates a change in an electrical potential of the cell membrane;
- and
- determining a status of the cell based at least in part on the spontaneous membrane potential vibration.
A method of analyzing a cell, comprising:
- capturing, over an elapsed time, a cell to generate a plurality of cell images;
- determining a spontaneous membrane potential vibration of the cell, wherein:
- determining the spontaneous membrane potential vibration comprises extracting, from the plurality of cell images, a variation in fluorescence intensity and a movement of the cell;
- and
- the spontaneous membrane potential vibration indicates a change in membrane potential and the change in membrane potential indicates a change in an electrical potential of the cell membrane;
- and
- determining a status of the cell based at least in part on the spontaneous membrane potential vibration.
Dependencies are inferred from the claim text.