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US 10,209,216 B2Granted
Electrospray ionization source and LC-MS interface
AssigneeBeijing Institute of Technology
InventorsWei Xu, Zezhen Zhang, Muyi He, Lili Hu
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Abstract
The present invention provides an electrospray ionization source, which includes: a capillary, including a spray tip; a first electrode which provides the spray tip with a spray voltage; and a second electrode. The electrical potential difference between the first electrode and the second electrode forms a separation electric field, which allows the electric field separation and electrospray ionization of the sample to be accomplished simultaneously, thereby improving the sensitivity of detection.
Claims17
An electrospray ionization source comprising:
- a capillary comprising a spray tip, wherein the capillary having an elongated body defining a longitudinal direction;
- a first electrode providing the spray tip of the capillary with a spray voltage;
- and
- a second electrode, wherein the electrical potential difference between the first electrode and the second electrode forms a separation electric field,
- wherein said first electrode and second electrode each has a front end, and wherein the distance of the front end of said second electrode from the spray tip of said capillary along the longitudinal direction is greater than the distance of the front end of said first electrode from the spray tip of said capillary along the longitudinal direction,
- wherein the front end of the second electrode does not extend beyond the spray tip and is spaced apart from the spray tip along the longitudinal direction, and
- wherein said capillary includes an opening on a side wall, and said first electrode includes a first portion and a second portion, the first portion disposed inside the capillary along the longitudinal direction, and the second portion passing through the side opening.
4 more elements
Dependencies are inferred from the claim text.