Solid-core ring-magnet
AssigneeAlpaqua Engineering, LLC
InventorOlaf Stelling
Life of this patent
Estimating the term…
Abstract
A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either case, a portion of cavity walls of the magnet are ring shaped, causing the magnetic field lines to emanate from the magnet in the shape of a ring. The diameter of the ring shaped cavities can be constant throughout, constant through a portion of the cavity, variant throughout, or variant through a portion of the cavity. The cavities open to the end of the magnet, and terminate toward the core of the magnet. Also provided are systems and kits having solid-core ring-magnets. Methods of purifying a macromolecule using the solid-core ring-magnets are also provided.
Claims22
A method for purifying macromolecules from a sample having a mixture in a vessel using a magnet wherein the macromolecules adhere to paramagnetic beads to form a complex under conditions to form a macromolecule-magnetic bead complex between the macromolecule and the magnetic beads;
- wherein the steps of the method comprise:
- a. separating the complex from the sample by placing the vessel at or near a cavity of the magnet;
- wherein the magnet comprises:
- i. a solid core having an inner mass of the magnet, a first end and a second end;
- ii. a first surface at or near the first end of the magnet;
- iii. a second surface at or near the second end of the magnet;
- iv. one or more cavities extending into the solid core at or near the first surface, the second surface, or both;
- wherein the one or more cavities each have a cavity wall and a portion of the cavity wall forms a ring shape;
- v. at least one side wall, wherein the side wall is in communication with the first surface and the second surface.
A method for separating macromolecules from a sample having a mixture in a vessel using a magnet wherein the macromolecules adhere to paramagnetic beads to form a complex under conditions to form a macromolecule-magnetic bead complex between the macromolecule and the magnetic beads;
- wherein the steps of the method comprise:
- a. placing the vessel at or near a cavity of the magnet to thereby separate the complex from the sample;
- wherein the magnet comprises:
- i. a solid core having an inner mass of the magnet, a first end and a second end;
- ii. a first surface at or near the first end of the magnet;
- iii. a second surface at or near the second end of the magnet;
- iv. one or more cavities at or near the first surface, the second surface, or both;
- wherein the one or more cavities each have at least a portion of a cavity wall that has a shape configured to form a magnetic field within a vessel when the vessel in use and is placed at or near the cavity;
- v. at least one side wall, wherein the side wall is in communication with the first surface and the second surface.
Dependencies are inferred from the claim text.