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US 10,208,099 B2Granted
Modified interleukin-7 protein
AssigneeGenexine, Inc.
InventorsSe Hwan Yang, Donghoon Choi, Hye Seong Lim
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Abstract
The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
Claims5
A modified interleukin-7 having the following structure:
- A-IL-7
- wherein A is an oligopeptide selected from the group consisting of glycine, methionine-methionine, glycine-glycine, methionine-glycine, glycine-methionine, methionine-methionine-methionine, methionine-methionine-glycine, methionine-glycine-methionine, glycine-methionine-methionine, methionine-glycine-glycine, glycine-methionine-glycine, glycine-glycine-methionine, glycine-glycine-glycine and methionine-methionine-methionine-methionine, and
- wherein the IL-7 is an interleukin 7.
Dependencies are inferred from the claim text.