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US 10,208,063 B2Granted
ACC inhibitors and uses thereof
AssigneeGilead Apollo, LLC
InventorsJeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
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Abstract
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.
Claims13
A compound of formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.