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US 10,207,271 B2Granted
Benchtop nucleic acid library preparation device and methods for using the same
AssigneeGencell Biosystems Ltd.
InventorsBrian Barrett, Noel Sirr, Brian Chawke, Kieran Curran, John Daly
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Abstract
Complete nucleic acid library preparation devices are provided. Aspects of the devices include: a thermal chip module comprising multiple CLC reaction wells; one or more plate locations; a robotically controlled liquid handler configured to transfer liquid between the one or more plate locations and the thermal chip module; and a bulk reagent dispenser configured to access each CLC reaction well of the thermal chip module.
Claims19
A complete bench-top nucleic acid library preparation device, the device comprising:
- a thermal chip module configured to receive a composite liquid cell (CLC) reaction cartridge;
- a CLC reaction cartridge positioned at the thermal chip module and comprising a plurality of wells;
- a consumable reagent location configured to receive a CLC nucleic acid library preparation reagent cartridge;
- a CLC nucleic acid library preparation reagent cartridge positioned at the consumable reagent location and comprising a plurality of wells;
- a sample location configured to receive a CLC sample cartridge;
- a CLC sample cartridge positioned at the sample location and comprising a plurality of wells;
- and
- a robotically controlled liquid handler configured to transfer liquid between the consumable reagent location, the sample location, and the thermal chip module, wherein the thermal chip module, the consumable reagent location, and the sample location are positioned on a main deck of the device, and
- wherein at least one well of the CLC reaction cartridge, the CLC nucleic acid library preparation reagent cartridge, or the CLC sample cartridge comprises a carrier fluid and an encapsulating fluid.
6 more elements
Dependencies are inferred from the claim text.