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US 10,207,060 B2Granted
Therapy appliance
AssigneeNLI GmbH
InventorsUlrich Koehler, Volker Gross, Keywan Ali Sohrabi
Life of this patent
Estimating the term…
Abstract
A therapy appliance, in particular for use for administering medicaments by nasal inhalation, includes a ventilation tube, on the input side of which is attached an aerosol generator connected to a medicament container, which aerosol generator is connected to a control unit. The ventilation tube is attached at the end to a nasal applicator.
Claims10
A therapy appliance for administering medicaments to a patient through nasal inhalation, comprising:
- a nasal applicator;
- a ventilation tube having an inlet side and being connected to the nasal applicator on the inlet side;
- medicament containers;
- an aerosol generator, said medicament containers and said aerosol generator being connected to an end-side of the ventilation tube;
- a control unit connected with the aerosol generator, said control unit being constructed to activate the aerosol generator according to an activation pattern, which is adjusted to a breathing pattern of the patient, thereby generating a respective aerosol bolus according to periodical integer multiples higher than 1 of a breathing cycle of the breathing pattern of the patient, wherein a size of aerosol particles of the aerosol bolus is between 0.1 and 3 μm, the control unit further constructed to limit an inhalation flow during supply of aerosol particles generated by the aerosol generator to 500 ml/s and to adjust an inhalation volume to more than 0.3 l;
- and
- a controllable respiration device constructed for continuously supplying oxygen and/or breathing air according to a predetermined breathing pattern during breathing of the patient, said predetermined breathing pattern being adjusted for targeted deposition of the aerosol in the nasopharynx and/or the lung of the patient.
4 more elements
A method for nasal aerosol inhalation into the lungs of a patient, comprising:
- controlling a respirator device to continuously supply breathing air to the airways of the patient via a ventilation tube according to a predetermined breathing pattern;
- and
- supplying aerosol particles with an aerosol nebulizer into a stream of the breathing air flowing in the ventilation tube, wherein the aerosol nebulizer is activated according to an activation pattern, said activation pattern being adjusted to the predetermined breathing pattern, so that a respective aerosol bolus is generated in according to integer multiples higher than 1 of a breathing cycle-of the breathing pattern, wherein a size of aerosol particles of the aerosol bolus is between 0.1 and 3 μm,
- wherein during the supplying of the aerosol particles an inhalation flow is limited to 500 ml/s and an inhalation volume is adjusted to more than 0.3 l, and
- wherein said predetermined breathing pattern is adjusted for targeted deposition of the aerosol in the nasopharynx and/or the lung of the patient.
2 more elements
Dependencies are inferred from the claim text.