Microcomposites for treatment of bone
AssigneeLoma Linda University
InventorsVictoria Maskiewicz, Gary Botimer, Serkan Inceoglu
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Abstract
Compositions having a drug-loaded microparticle and bone cement and methods of making such compositions are disclosed. Also disclosed are methods of employing such compositions for the treatment of injected joint spaces and bone disease.
Claims17
A composition, comprising a drug-loaded microparticle comprising at least one drug and a porous ceramic, wherein the drug-loaded microparticle has a random, non-arrayed pore structure into which the at least one drug is embedded, wherein the drug-loaded microparticle is dispersed in a bone cement, and wherein the porous ceramic comprises silica.
A method of treating a bone condition, comprising locally administering a composition comprising a drug-loaded microparticle comprising at least one drug and a porous ceramic, wherein the drug-loaded microparticle has a random, non-arrayed pore structure into which the at least one drug is embedded, wherein the drug-loaded microparticle is dispersed within a bone cement, and wherein the porous ceramic comprises silica.
Dependencies are inferred from the claim text.