Photodynamic therapy composition

A pharmaceutical composition comprising a phthalocyanine compound or targeted conjugate thereof having the formula (I):

• wherein X1 is hydrogen or includes a targeting moiety directly or indirectly coupled or conjugated to the thiol group;
• R1, R4, R5, R8, R9, R12, R13, and R16 are each independently selected from the group consisting of hydrogen, halogen, nitro, cyano, hydroxyl, thiol, amino, and methyl;
• R2, R3, R6, R7, R10, R11, R14, and R15 are each independently selected from the group consisting of hydrogen, halogen, nitro, cyano, hydroxyl, thiol, amino, carboxy, aryl, heteroaryl, carbocyclyl, heterocyclyl, C1-6 alkyl, C1-6 alkenyl, C1-6 alkynyl, C1-6 alkoxy, C1-6 acyl, C1-6 alkylcarbonyloxy, C1-6 carbocyclylalkyl, C1-6 aminoalkyl, C1-6 alkylamino, C1-6 thioalkyl, C1-6alkylthio, C1-6hydroxyalkyl, C1-6 alkyloxycarbonyl, C1-6 alkylaminocarbonyl, and C1-6 alkylcarbonylamino;
• and pharmaceutically acceptable salts thereof.