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US 10,207,000 B2Granted
Stable aqueous formulations of adalimumab
AssigneeCoherus Biosciences, Inc.
InventorsMark Manning, Robert W. Payne
Life of this patent
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Abstract
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
Claims11
A stable aqueous pharmaceutical composition comprising:
- i) adalimumab;
- ii) a single buffer;
- iii) a surfactant;
- and
- iv) a tonicity modifier,
- wherein the composition is free of mannitol and has a pH of about 5 to about 6.
3 more elements
Dependencies are inferred from the claim text.