MDR E. coli specific antibody
AssigneeArsanis Biosciences GmbH
InventorsEszter Nagy, Gábor Nagy, Valéria Szijárto, Zoltán Magyarics, Irina Mirkina, Luis Guachalla, Adriana Badarau, Gerhild Zauner, Jolanta Lukasiewicz
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Abstract
The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.
Claims23
A composition comprising an O25b antigen having the structure:
- and an adjuvant, a liposome or a cationic peptide.
An immunogenic composition comprising an effective amount of an O25b antigen having the structure:
- and an adjuvant.
A vaccine formulation comprising an effective amount of an O25b antigen having the structure:
- and an adjuvant, wherein the vaccine formulation is formulated for parental administration.
Dependencies are inferred from the claim text.