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US 10,206,985 B2Granted
WT1 peptide cancer vaccine composition for mucosal administration
AssigneesNitto Denko Corporation, Osaka University
InventorsDaisuke Asari, Kyohei Matsushita, Arimichi Okazaki, Yoshiki Maeda, Katsuyuki Okubo, Mitsuhiko Hori, Haruo Sugiyama
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Abstract
The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a cellular immunity induction promoter. The composition efficiently induces cellular immunity against a cancer in a subject.
Claims22
A method for inducing cellular immunity in a subject, which comprises mucosally administering to the subject a cancer vaccine composition comprising:
- (i) a WT1 peptide and/or a modified WT1 peptide;
- (ii) a first cellular immunity induction promoter comprising a TLR7 ligand and a helper peptide.
Dependencies are inferred from the claim text.