US 10,206,964 B2 · Synergistic anti-inflammatory compositions comprising Boswellia serrata extract

Abstract

The present invention discloses synergistic nutraceutical or pharmaceutical or dietary supplement anti-inflammatory compositions comprising therapeutically effective combination of an extract selectively enriched in 3-O-acetyl-1 1-keto-β-boswellic acid (AKBA) derived from Boswellia serrata and Boswellia serrata non-acidic resin extract (BNRE). The composition(s) can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, endothelial dysfunction and the like. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.

Claims14

Dependent claims

An anti-inflammatory composition, comprising a therapeutically effective amount of a combination of:

from 10% to 90% by weight of the combination of a Boswellia serrata extract selectively enriched in 3-O-acetyl-11-keto-β-boswellic acid (AKBA);
and
from 10% to 90% by weight of the combination of a Boswellia serrata resin non-acidic, water-immiscible organic solvent extract (BNRE) obtained by selectively removing acidic compounds from a Boswellia serrata gum resin extract.

Dependencies are inferred from the claim text.

Facts

Application

14/735,360Filed 10 Jun 2015 · continuation

Priority

IN 2229/CHE/200815 Sep 2008

Published

US 2015/0290270 A115 Oct 2015

Granted

19 Feb 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification23 codes

A61K 36/324
Burseraceae: boswellia, e.g. frankincense
A61P 1/00
Drugs for disorders of the alimentary tract or the digestive system
A61P 1/02
Drugs for disorders of the alimentary tract or the digestive system: stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A61P 1/04
Drugs for disorders of the alimentary tract or the digestive system: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of…

Family

PCT/IN2009/000505Parent of this continuation · filed 14 Sep 2009

US 2015/0290270 A1Pre-grant publication · published 15 Oct 2015

Application13/062,066Parent of this continuation

US 9,101,599 B2Parent of this continuation

US 2011/0159120 A1Published application

US 10,206,964 B2This patent

From the US filing history. Foreign family members aren’t listed.

Synergistic anti-inflammatory compositions comprising Boswellia serrata extract

Life of this patent

Synergistic anti-inflammatory compositions comprising Boswellia serrata extract

Life of this patent

Abstract

Claims14