Implants and methods for treating inflammation-mediated conditions of the eye
AssigneeAllergan, Inc.
InventorsVernon G. Wong, Mae W. L. Hu
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Abstract
Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 μg/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 μg/ml dexamethasone for at least about three weeks.
Claims6
A method for treating an inflammation-mediated condition of the eye comprising:
- implanting into the vitreous of an eye in need thereof a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant is produced by an extrusion method, wherein the total weight of the implant is about 500-1000 μg, and wherein the inflammation-mediated condition of the eye is macular edema.
Dependencies are inferred from the claim text.