Non-hormonal steroid modulators of NF-kB for treatment of disease
AssigneeReveraGen BioPharma, Inc.
InventorsJohn M. McCall, Eric Hoffman, Kanneboyina Nagaraju
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Abstract
The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
Claims14
A method for reducing the symptoms of a disease selected from atherosclerosis, hypercholesterolemia, chronic heart failure, ischemia/reperfusion, angina pectoris, and myocarditis, comprising administering, to a patient in need thereof, a pharmaceutical composition comprising a pharmaceutically acceptable carrier together with a compound having the structure:
- and/or a salt thereof.
Dependencies are inferred from the claim text.