Back to results
US 10,206,930 B2Granted
Methods for treating T-cell acute lymphoblastic leukemia
AssigneeNew York University
InventorsIannis Aifantis, Panagiotis Ntziachristos
Life of this patent
Estimating the term…
Abstract
The present invention is directed to methods of treating T-ALL that involve administering an inhibitor of jumonji D3 (JMJD3) demethylase. Another embodiment of the invention relates to methods inhibiting T-ALL cell proliferation and/or survival that involves administering an inhibitor of jumonji D3 (JMJD3) demethylase to a population of T-ALL cells.
Claims14
A method of treating T-cell acute lymphoblastic leukemia in a subject, said method comprising:
- selecting a subject having T-cell acute lymphoblastic leukemia and
- administering, to the selected subject, an inhibitor of jumonji D3 (JMJD3) demethylase activity at a dosage effective to treat the T cell acute lymphoblastic leukemia in the subject.
A method of inhibiting T-cell acute lymphoblastic leukemia cell proliferation and/or survival, said method comprising:
- administering to a population of T-cell acute lymphoblastic leukemia cells an inhibitor of JMJD3 at a dosage effective to inhibit the T-cell acute lymphoblastic leukemia cell proliferation and/or survival.
Dependencies are inferred from the claim text.