Topical compositions for pain relief, manufacture and use
AssigneeVizuri Health Sciences LLC
InventorsPhilip J. Birbara, Daniel Bucks
Life of this patent
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Abstract
The present invention relates to TRPV1 selective agonist compositions including a capsaicinoid, a surfactant and an extended release agent, and to methods of manufacture and methods of providing pain relief as well as treating a variety of disorders with such compositions.
Claims10
A method of treating pain in a mammal suffering from pain comprising topically administering a composition to said mammal, the composition comprising
- i) 0.075-20% by weight of a capsaicinoid,
- ii) an extended release agent to slow the release of said capsaicinoid from said composition upon administration of said composition to a mammal, and
- iii) a surfactant.
A method of treating a capsaicin responsive condition in a mammal suffering from said condition comprising topically administering a composition to said mammal, the composition comprising
- i) 0.075-20% by weight of a capsaicinoid,
- ii) an extended release agent to slow the release of said capsaicinoid from said composition upon administration of said composition to a mammal, and
- iii) a surfactant.
A method of treating itching in a mammal comprising topically administering a composition, the composition comprising
- i) 0.075-20% by weight of a capsaicinoid,
- ii) an extended release agent to slow the release of said capsaicinoid from said composition upon administration of said composition to a mammal, and
- iii) a surfactant.
A method of formulating an aqueous capsaicinoid formulation comprising:
- i) dissolving a capsaicinoid in a surfactant to form a solution, and
- ii) adding hyaluronic acid to the solution.
A method of producing an aqueous topical formulation of capsaicin comprising:
- i) mixing a capsaicinoid and a surfactant and ethanol, and
- ii) adding hyaluronic acid.
Dependencies are inferred from the claim text.