Anti-acne formulation
AssigneeEnvy Medical, Inc.
InventorsLyndon Garcines, Susan Goldsberry, Senad Ibrulj
Life of this patent
Estimating the term…
Abstract
A composition for the treatment of acne includes hydrolyzed Psoralea Corylifolia, containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In a specific implementation, the composition is a water-based acne gel. In a specific implementation, a composition includes Bakutrol™, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.
Claims20
A method of preparing an aqueous mixture comprising:
- providing a first mixture, wherein the first mixture is uniformly mixed, is aqueous, and at a temperature of about 40 to about 45 degrees Celsius;
- providing an unsolubilized hydrolyzed Psoralea corylifolia extract;
- and
- solubilizing the unsolubilized hydrolyzed Psoralea corylifolia extract comprising:
- mixing the unsolubilized hydrolyzed Psoralea corylifolia extract, bisabolol, and polysorbate 20 to obtain a second mixture, and
- adding the second mixture to the first mixture to obtain a third mixture, wherein the third mixture is at a temperature from 40 to 45 degrees Celsius, and the third mixture is an aqueous mixture comprising a solubilized hydrolyzed Psoralea corylifolia extract.
A method of preparing an aqueous mixture comprising mixing first constituents to obtain a first mixture:
- solubilizing an unsolubilized hydrolyzed Psoralea corylifolia extract to obtain a solubilized hydrolyzed Psoralea corylifolia extract comprising mixing the unsolubilized hydrolyzed Psoralea corylifolia extract and bisabolol to obtain a second mixture, and adding the second mixture to the first mixture at a temperature from 40 to 45 degrees Celsius to obtain a third mixture, wherein the third mixture comprises the solubilized hydrolyzed Psoralea corylifolia extract;
- allowing the third mixture to cool to about 35 degrees Celsius;
- and
- obtaining an aqueous mixture that is a combination of the first and second mixtures, wherein the aqueous mixture is an anti-acne formulation.
A method of preparing a mixture comprising:
- mixing first constituents to obtain a first mixture at a temperature of about 40 to about 45 degrees Celsius;
- solubilizing an unsolubilized bakuchiol to obtain a solubilized hydrolyzed bakuchiol comprising mixing the unsolubilized hydrolyzed bakuchiol and bisabolol to obtain a second mixture, and adding the second mixture to the first mixture at a temperature from 40 degrees Celsius to 45 degrees Celsius to 40 degrees Celsius to obtain a third mixture, wherein the third mixture comprises the solubilized hydrolyzed bakuchiol;
- allowing the third mixture to cool to a temperature less than that at which the second mixture was added to the first mixture;
- and
- obtaining a mixture that is a combination of the first and second mixtures, wherein the aqueous mixture is an anti-acne formulation.
Dependencies are inferred from the claim text.