Build sequences for mechanosynthesis

A method of employing a mechanosynthetic build sequence, comprising:

• a. loading a mechanosynthetic build sequence into a computer memory that is connected to a computer, said build sequence comprising an ordered sequence of mechanosynthetic reactions for which the degree of reliability in positioning feedstock at a specific site, at a given temperature and with realistic equipment capabilities including sub-angstrom positional accuracy, has been calculated, the build sequence having been determined capable of creating a workpiece with a desired degree of reliability, wherein said computer is connected to a positional device that meets the equipment capabilities used to calculate reaction reliability;
• and
• b. operating said positional device under control of said computer at a temperature no greater than the given temperature used to calculate reaction reliability so as to carry out a plurality of mechanosynthetic reactions from said build sequence.