A system for preparing nanoparticles by supercritical hydrothermal synthesis, comprising a first reactant modulation pool (1), a steam generator (2), a back pressure valve (4), a gas-liquid separator (5), a centrifugal separator (6), an oil-water separator (7), a heat regenerator (9), a heating furnace (10), a first material pump (11), a premixer (12), a mixer (13), a supercritical hydrothermal synthesis reactor (14), a second material pump (16), a pure water pump (17), a pure water storage tank (18), a second reactant storage pool (19), and a waste heat power generation system (20), wherein:
- an outlet of the first reactant modulation pool (1) is communicated with an inlet of the first material pump (11), an outlet of the first material pump (11) is communicated with a first inlet of the premixer (12);
- an outlet of the second reactant storage pool (19) is communicated with an inlet of the second material pump (16), an outlet of the second material pump (16) is communicated with a second inlet of the premixer (12), and an outlet of the premixer (12) is communicated with a vertical inlet of the mixer (13);
- an outlet of the pure water storage tank (18) is communicated with an inlet of the pure water pump (17), an outlet of the pure water pump (17) is communicated with a low-temperature section inlet of the heating furnace (10), a low-temperature section outlet of the heating furnace (10) is communicated with a casing side inlet of the heat regenerator (9), a casing side outlet of the heat regenerator (9) is communicated with a high-temperature section inlet of the heating furnace (10), a high-temperature section outlet of the heating furnace (10) is communicated with a high-temperature water inlet of the mixer (13), a vertical outlet of the mixer (13) is communicated with an inlet of the supercritical hydrothermal synthesis reactor (14), an outlet of the supercritical hydrothermal synthesis reactor (14) is communicated with a pipe side inlet of the heat regenerator (9), a pipe side outlet of the heat regenerator (9) is divided into two portions, one portion is communicated with an inlet of a heat exchange coil in the first reactant modulation pool (1), the other portion is merged with an outlet of the heat exchange coil and then communicated with an inlet of the steam generator (2) in the waste heat power generation system (20), an outlet of the steam generator (2) is communicated with an inlet of the back pressure valve (4), an outlet of the back pressure valve (4) is communicated with an inlet of the centrifugal separator (6), an outlet of the centrifugal separator (6) is communicated with an oil-phase inlet of the oil-water separator (7), an oil-phase outlet of the oil-water separator (7) is communicated with an inlet of the second reactant storage pool (19).