Papillomavirus pseudoviruses for detection and therapy of tumors
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsJeffrey Roberts, Douglas R. Lowy, John T. Schiller
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Abstract
Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP).
Claims8
A method comprising administering to cancer cells in a subject, a papilloma pseudovirus that comprises a fluorescent dye or a papilloma virus-like particle (VLP) that comprises a fluorescent dye, and exposing the fluorescent dye in the cancer cells in the subject to an excitation wavelength of light.
A method comprising administering to cancer cells in an eye of a subject, a papilloma pseudovirus chemically coupled to a fluorescent dye or a papilloma virus-like particle (VLP) chemically coupled to a fluorescent dye, and exposing the fluorescent dye in the cancer cells in the subject to an excitation wavelength of light.
Dependencies are inferred from the claim text.