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US 10,188,720 B2Granted
Recombinant Marek's disease viruses and uses thereof
AssigneeCeva Sante Animale
InventorsMotoyuki Esaki, Shuji Saitoh, Takanori Sato
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Abstract
The present invention relates recombinant viruses and the uses thereof. More particularly, the invention relates to novel recombinant Marek's disease viruses encoding polypeptide(s) of interest, and their use to express or deliver such polypeptides to animals, particularly poultry. The invention is particularly suited to vaccinate poultry against avian pathogens.
Claims20
A recombinant Marek's disease virus of serotype 1 (MDV1) which comprises (1) a promoter of 274 nucleotides in length consisting of SEQ ID NO:
- 5 or consisting of a sequence having at least 90% sequence identity to SEQ ID NO:
- 5 and exhibiting transcriptional promoter activity and (2) under the control of said promoter, a recombinant nucleotide sequence encoding a polypeptide.
Dependencies are inferred from the claim text.