Methods for preparing aqueous suspension of precious metal nanoparticles
AssigneeImra America, Inc.
InventorsYuki Ichikawa, Andrius Marcinkevicus, Masayuki Ito, Wei Qian
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AssigneeImra America, Inc.
InventorsYuki Ichikawa, Andrius Marcinkevicus, Masayuki Ito, Wei Qian
Estimating the term…
The present disclosure is directed to methods of preparing stable suspensions of precious metal nanoparticles and methods for attaching bio-molecules to the nanoparticles. The formation of nanoparticles can be accomplished by either chemical synthesis or pulsed laser ablation in a liquid. The present disclosure reveals the importance of controlling the conductivity of the dispersion medium during pulsed laser ablation in a liquid to control the particle size of the nanoparticles. The present disclosure also reveals the importance of adjusting and maintaining the conductivity in a range of 25 μS/cm or less during storage of the nanoparticles and just prior to performing bioconjugation reactions. The control of conductivity is an important process for maintaining the nanoparticles as a stable non-aggregated colloidal suspension in a dispersion medium.
A colloidal suspension comprising;
Dependencies are inferred from the claim text.