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US 10,179,896 B2Granted
Method and system for a bioartificial organ
AssigneeBaker Group, LLP
InventorsMichael John Baker, Shelby K. Suckow
Life of this patent
Estimating the term…
Abstract
Methods and systems are provided for a stem cell organ device including an array of alternating stem cell channels and fluid channels. In one example, a method may include loading a stem cell channel with stem cells and flowing blood through a fluid channel in order to allow an exchange of molecules between the stem cells and the blood.
Claims19
A stem cell organ device, comprising:
- a first channel adapted to house a plurality of cells, wherein a width of the first channel is less than 100 μm;
- a second channel;
- a membrane arranged between the first channel and the second channel;
- and
- a first inlet manifold coupled to the first channel;
- wherein the first channel and the second channel comprise a plurality of ridges facing the membrane, wherein the ridges are of variable size and shape.
3 more elements
A stem cell organ device, comprising:
- a first layer including a first plurality of channels adapted to house a plurality of cells;
- a second layer including a second plurality of channels, where each channel of the second plurality of channels is aligned with a corresponding channel of the first plurality of channels;
- wherein a width of each of the plurality of channels is less than 100 μm;
- and
- a semi-permeable membrane positioned between the first layer and the second layer;
- wherein each of the plurality of channels comprises a plurality of ridges facing the semi-permeable membrane, wherein the ridges are of variable size and shape.
3 more elements
A stem cell organ device, comprising:
- a first layer including a first plurality of channels adapted to house a plurality of cells and a first inlet manifold, wherein a plurality of stem cell guides are interspersed on an inner surface of the first inlet manifold;
- and
- wherein the stem cell guides are at least one of an etching, protrusion, groove, ingot, or stamp;
- a second layer including a second plurality of channels, where each channel of the second plurality of channels is aligned with a corresponding channel of the first plurality of channels;
- and
- a semi-permeable membrane positioned between the first layer and the second layer.
3 more elements
Dependencies are inferred from the claim text.