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US 10,175,170 B2Granted
Metal coating of rare earth nano-phosphors and uses thereof
AssigneeThe Regents of the University of California
InventorsIan M. Kennedy, Sudheendra Lakshmana
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Abstract
Core-shell nanoparticles comprises a phosphorescent core and metal shell comprising at least two metals The phosphorescent core may comprise an up converting phosphor. The phosphorescent core may comprise a trivalent rare earth cation. The phosphorescent core further may comprise a monovalent alkali metal. The phosphorescent core may optionally comprises a second and also optionally a third trivalent rare earth cation.
Claims12
A nanoparticle comprising:
- a phosphorescent core comprising:
- Er3+, Y3+, Yb3+, sodium cation, citrate anion, and fluoride anion;
- and
- a streptavidin (SA) or streptavidin-tetramethylrhodamine (SA-TMR) tag;
- and
- a metal shell comprising Au and Ag;
- and
- a magnetic component comprising Fe3O4.
5 more elements
A method of producing a nanoparticle comprising a phosphorescent core and a two-metal shell, the method comprising:
- mixing Er3+, Y3+, and Yb3+ with sodium citrate to create a citrate solution;
- mixing the citrate solution with sodium fluoride to create a first mixture;
- heating the first mixture;
- adding Au to the first mixture to create a second mixture;
- adding Ag to the second mixture;
- optionally adding Au and adding Ag one or two more times, thereby producing the nanoparticle.
3 more elements
Dependencies are inferred from the claim text.