Devices and methods for dissociating a biological tissue sample
AssigneeBecton, Dickinson and Company
InventorsAaron J. Middlebrook, Smita Ghanekar, Brian David Warner, Albert Mach, David Vrane
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Abstract
Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators may include a housing having a distal end and a proximal end, a cutting blade positioned at the distal end of the housing and a tissue actuator configured to be displaced along a longitudinal axis within the housing. Also provided are methods of using the tissue dissociators, as well as kits including the tissue dissociators.
Claims20
A method of dissociating a biological tissue, the method comprising:
- inserting a biological tissue into a housing of a tissue dissociator, wherein the tissue dissociator comprises:
- a housing having an open distal end and a proximal end;
- a cutting blade positioned at the open distal end of the housing;
- a tissue actuator configured to be displaced along a longitudinal axis within the housing;
- and
- pressing the biological tissue against the cutting blades by displacing the tissue actuator from the proximal end to the distal end of the housing in a manner sufficient to produce a dissociated biological tissue comprising components of identical shape and size.
A kit comprising:
- a housing having an open distal end and a proximal end;
- a cutting blade positioned at the open distal end of the housing;
- and
- a tissue actuator configured to be displaced along a longitudinal axis within the housing.
A tissue dissociator comprising:
- a housing comprising an open distal end and a proximal end;
- a cutting blade positioned at the open distal end of the housing;
- and
- a tissue actuator configured to be displaced along a longitudinal axis within the housing.
Dependencies are inferred from the claim text.