Virus causing respiratory tract illness in susceptible mammals
AssigneeErasmus University Medical Center Rotterdam
InventorsJan Cornelius De Jong, Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Groen
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Abstract
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
Claims10
A kit for determining the presence of metapneumovirus (MPV) in a mammalian subject, the kit comprising:
- a DNA probe of at least 10 nucleotides that hybridizes under stringent conditions to a target polynucleotide,
- wherein the target polynucleotide is a contiguous portion of a sequence encoding a polypeptide that is at least 90% identical to SEQ ID NO:8 or the complement of the sequence, and
- wherein the DNA probe does not hybridize under stringent conditions to a polynucleotide from avian pneumovirus (APV).
A kit for determining the presence of metapneumovirus (MPV) in a mammalian subject, the kit comprising:
- a DNA probe of at least 25 nucleotides that is at least 90% identical to a contiguous portion of a sequence encoding a polypeptide that is at least 90% identical to SEQ ID NO:8 or A the complement of the sequence.
Dependencies are inferred from the claim text.