Microorganisms and methods for the production of aniline

A method for producing aniline comprising:

• (a) culturing a non-naturally occurring Escherichia coli under conditions and for a sufficient period of time to produce aniline, wherein the non-naturally occurring Escherichia coli comprises an aniline pathway, the aniline pathway comprising an anthranilate synthase, a 3-dehydroquinate synthase, a 3-dehydroquinate dehydratase, a shikimate dehydrogenase or a quinate/shikimate dehydrogenase, a shikimate kinase, a 3-phosphoshikimate-1-carboxyvinyltransferase, a chorismate synthase, and an anthranilate decarboxylase, wherein the non-naturally occurring Escherichia coli comprises at least two exogenous nucleic acids encoding at least two enzymes of the aniline pathway selected from the group consisting of the 3-dehydroquinate synthase, the anthranilate synthase, the 3-dehydroquinate dehydratase, the shikimate dehydrogenase or the quinate/shikimate dehydrogenase, the shikimate kinase, the 3-phosphoshikimate-1-carboxyvinyltransferase, and the chorismate synthase, wherein the anthranilate decarboxylase in the non-naturally occurring Escherichia coli is endogenous, and wherein the aniline pathway enzymes are expressed in a sufficient amount to produce aniline;
• and
• (b) isolating aniline.