Optimizing mifepristone levels for Cushing's patients
AssigneeCorcept Therapeutics, Inc.
InventorsJoseph Belanoff, Coleman Gross
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Abstract
The present invention provides a method for optimizing levels of mifepristone in a patient suffering from Cushing's syndrome. The method comprises the steps of treating the patient with seven or more daily doses of mifepristone over a period of seven or more days; testing the serum levels of the patient to determine whether the blood levels of mifepristone are greater than 1631 ng/mL; and adjusting the daily dose of the patient to achieve mifepristone blood levels greater than 1631 ng/mL.
Claims9
A method for improving efficacy of mifepristone treatment in a patient suffering from Cushing's syndrome, the method comprising:
- treating the patient with seven or more daily doses of mifepristone over a period of seven or more days;
- testing the serum levels of the patient to determine whether the blood levels of mifepristone are greater than 1631 ng/mL;
- and
- adjusting the daily dose of the patient to achieve mifepristone blood levels greater than 1631 ng/mL,
- with the proviso that the patient is not already suffering from a condition indicated for treatment with mifepristone, thereby improving the efficacy of mifepristone treatment for the patient suffering from Cushing's syndrome.
Dependencies are inferred from the claim text.