Tunable nanofiber filter media and filter devices

A diffusion filter for dialysis, comprising:

• a housing defining an interior space, the housing having defined therein first and second inlets and first and second outlets, the inlets and outlets in fluid communication with the interior space;
• an assembly of laminas disposed within the interior space, the lamina assembly comprising:
• a plurality of filter laminas, each filter lamina including a first and second slot defined therethrough, and
• a plurality of spacer laminas, each spacer lamina having a central aperture defined therethrough;
• the filter and spacer laminas arranged alternatingly in a stack wherein the central aperture of each spacer lamina defines an interlaminar space between opposing surfaces of corresponding adjacent filter laminas, the interlaminar space in fluid communication with the first and second slots of said adjacent filter laminas such that the first slots form a first flow path extending through the stack from the first inlet to the first outlet, and the second slots form a second flow path extending through the stack from the second inlet to the second outlet;
• a plurality of diffusion zones formed in the interlaminar space, each diffusion zone comprising an array of nanofibers extending into the interlaminar space from a portion of a corresponding adjacent filter lamina such that the array of nanofibers separates the first and second flow paths throughout the interlaminar flow space;
• wherein a first fluid flowed through the first flow path interfaces across said diffusion zones with a second fluid flowed through the second flow path.