Back to results
US 10,156,559 B2Granted
Lipocalin fusion partners
AssigneeFred Hutchinson Cancer Research Center
InventorsJames Olson, Christopher Mehlin, Colin Correnti, Roland Strong
Life of this patent
Estimating the term…
Abstract
Methods and systems for producing fusion proteins and peptides are disclosed. Fusion proteins and peptides created using the methods are also provided. Also provided are methods of using the fusion proteins and peptides produced according to the present disclosure.
Claims22
A method for producing a fusion protein, the method comprising:
- expressing, in a cell, a fusion protein, the fusion protein comprising:
- a knotted-peptide selected from PMP-D2, potato carboxypeptidase inhibitor, huwentoxin, imperatoxin, epiregulin, midkine, bubble protein and conotoxin CIVC;
- and
- a siderocalin protein selected from human siderocalin, murine siderocalin, chicken Ex-FABP, and quail Q83, thereby producing the fusion protein.
1 more element
A composition comprising a fusion protein, the fusion protein comprising:
- a knotted-peptide selected from PMP-D2, potato carboxypeptidase inhibitor, huwentoxin, imperatoxin, epiregulin, midkine, bubble protein and conotoxin CIVC;
- and
- a siderocalin protein selected from human siderocalin, murine siderocalin, chicken Ex-FABP, and quail Q83.
Dependencies are inferred from the claim text.