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US 10,155,952 B2Granted
Method for producing target substance
AssigneeAjinomoto Co., Inc.
InventorsKazuteru Yamada, Yoshihiko Hara
Life of this patent
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Abstract
A method for producing a target substance is provided. A target substance is produced by culturing a coryneform bacterium, which is able to produce a target substance, and which also has an improved ability to assimilate xylose as a result of the introduction of a mutation into a coding region and/or an expression control region of the NCgl2954 gene on the chromosome of the bacterium. The culture is conducted in a medium containing xylose, and the target substance can be collected from the medium.
Claims21
A method for producing a target substance comprising:
- culturing a coryneform bacterium having an ability to produce a target substance in a medium containing xylose to produce and accumulate the target substance in the medium;
- and
- collecting the target substance from the medium,
- wherein the bacterium has been modified so that the ability of the bacterium to assimilate xylose is improved as compared with a non-modified bacterium by attenuation of expression or disruption of the NCgl2954 gene on the chromosome of the bacterium.
1 more element
Dependencies are inferred from the claim text.