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US 10,155,947 B2Granted
Method for inhibiting Ebola virus via miRNA
AssigneeJiangsu Micromedmark Biotech Co., Ltd.
InventorsChenyu Zhang, Hongwei Liang, Zhen Zhou, Ke Zeng, Xi Chen
Life of this patent
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Abstract
Provided are a method and use of microRNA MiR-2911 in regulating an ebola virus. Particularly provided are a method and use of isolated microRNA MiR-2911 in regulating an ebola virus protein gene.
Claims8
A method for inhibiting expression of a protein of an Ebola virus comprising:
- administering MIR-2911 or an extract or a composition containing MIR-2911 to a subject in need thereof,
- wherein the protein of the Ebola virus is GP, or VP40, or a combination thereof,
- the subject is infected with the Ebola virus, and
- the MIR-2911 or the extract or the composition inhibits expression of GP and VP40 of the Ebola virus in the subject.
1 more element
A method for inhibiting destruction or death of endothelial cells caused by GP of Ebola virus, wherein the method comprises the following step:
- administering MIR2911 or an extract or a composition containing MIR2911 to a subject in need thereof.
A method for inhibiting Ebola virus, wherein the method comprises the step of contacting miR2911 with Ebola virus or cells infected with Ebola virus.
Dependencies are inferred from the claim text.