Peptides having anti-inflammatory properties
AssigneeRiptide Bioscience, Inc.
InventorsJesse Jaynes, Henry Wilfred Lopez, George R. Martin, Clayton Yates, Charles Garvin
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Abstract
Aspects of the present invention relate to peptides having anti-inflammatory activity, compositions containing one or more of the peptides, and use of the peptides to treat conditions associated with excessive inflammation in animals, particularly humans and other mammals.
Claims9
An immunomodulatory peptide of 18 amino acid residues or less in length, wherein the peptide has a sequence defined by one of the formulae:
- [Y1aY1b]-[X1aX1b]-[Y2aY2b]-[X2aX2b]-[Y3a]-[X3a];
- and
- [X3a]-[Y3a]-[X2bX2a]-[Y2bY2a]-[X1bX1a]-[Y1bY1a];
- wherein:
- Y1a, Y1b, Y2a, Y2b and Y3a are each phenylalanine;
- and
- X1a, X1b, X2a, X2b and X3a are each independently selected from lysine and arginine.
An immunomodulatory peptide of 18 amino acid residues or less in length, the peptide comprising the amino acid sequence KFKKAFKKAF (SEQ ID NO:148) or FFRKFAKRFK (SEQ ID NO:122).
Dependencies are inferred from the claim text.