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US 10,144,949 B2Granted
Systems and methods for electrochemical aspartate transaminase (AST) and alanine transaminase (ALT) detection and quantification
AssigneePolymer Technology Systems, Inc.
InventorsGary L. Hughes, Aniruddha Patwardhan
Life of this patent
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Abstract
A system for electrochemically detecting AST and ALT includes a first sampler for producing pyruvate from ALT and a second sampler for producing pyruvate from AST. The system further includes an electrochemical test strip for receiving processed samples from the first and second samplers, the processed samples containing pyruvate. The system further includes a meter for reading the electrochemical test strip and indicating an amount of AST and ALT in the sample.
Claims5
A system for electrochemically detecting AST and ALT, the system comprising:
- a first sampler containing L-Alanine+alpha-Ketoglutarate, said first sampler receiving a first blood sample and producing pyruvate from ALT in the first blood sample;
- a second sampler containing L-Aspartic acid+alpha-Ketoglutarate, said second sampler receiving a second blood sample and producing pyruvate from AST in the second blood sample;
- at least one electrochemical test strip containing, pyruvate oxidase from E. coli, phosphate and ferricyanide receiving the first and second blood samples from the first and second samplers;
- and
- a meter reading the at least one electrochemical test strip and indicating a amount of ALT and AST in the first and second blood samples.
2 more elements
Dependencies are inferred from the claim text.