Method using an Y1 receptor activator for treating an anticancer agent-induced nephrotoxic injury
AssigneeKyungpook National University Industry-Academic Cooperation Foundation
InventorsJae Sung Bae, Hee Kyung Jin, Min Hee Park
Life of this patent
Estimating the term…
Abstract
There is provided a method for treating or reducing an anticancer agent-induced nephrotoxic injury, the method comprising the step of administering a Y1 receptor activator in an amount effective to treat or reduce the anticancer agent-induced nephrotoxic injury in a subject. Further, there is provided a method for screening an agent for treating or reducing an anticancer agent-induced nephrotoxic injury, the method comprising (a) applying a candidate material to a test sample of renal tissues or cells; and (b) identifying a Y1 receptor signaling in the test sample of renal tissues or cells.
Claims3
A method for treating or reducing an anticancer agent-induced nephrotoxic injury in a subject, the method comprising the step of administering a Y1 receptor activator in an amount effective to treat or reduce the anticancer agent-induced nephrotoxic injury in a subject,
- wherein the Y1 receptor activator is Neuropeptide Y (NPY) or [Leu31 Pro34]NPY,
- wherein the anticancer agent is at least one selected from the group consisting of cisplatin, carboplatin and oxaliplatin.
Dependencies are inferred from the claim text.