Back to results
US 10,137,082 B2Granted
Hydrogel microparticle scaffold with gradients of degradability and methods thereof
AssigneeWashington University
InventorsDonald L. Elbert, Jacob Roam
Life of this patent
Estimating the term…
Abstract
Disclosed herein is a device and method for regenerating tissue using a modular scaffold having a gradient of enzymatic degradability. The disclosure further relates to scaffolds made of microparticles comprising a cross-linked water-soluble polymer or cross-linked water-soluble polymers and a process for forming thereof.
Claims18
A modular scaffold comprising a plurality of hydrogel microparticles, wherein the hydrogel microparticles are crosslinked together with at least some crosslinks having tunable rates of enzymatic degradation, wherein the crosslinks is the plasmin sensitive peptide sequence Ac-GCGGVRNGGK-NH2.
Dependencies are inferred from the claim text.