Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same

A device for collecting and analyzing vapor condensate (VC) sample, comprising:

• a collection plate and a cover plate, wherein:
• i. the plates are movable relative to each other into different configurations;
• ii. one or both plates are flexible;
• iii. each of the plates has, on its respective surface, a sample contact area for contacting a vapor condensate (VC) sample that contains an analyte;
• iv. one or both of the plates comprise spacers that are fixed with a respective plate, wherein the spacers have a predetermined substantially uniform height and a predetermined constant inter-spacer distance and wherein at least one of the spacers is inside the sample contact area;
• wherein one of the configurations is an open configuration, in which:
• the two plates are either completely or partially separated apart, the spacing between the plates is not regulated by the spacers, and the VC sample is deposited on one or both of the plates;
• and
• wherein another of the configurations is a closed configuration which is configured after the VC sample deposition in the open configuration;
• and in the closed configuration:
• at least a part of the VC sample is between the two plates and in contact with the two plates, and has a highly uniform thickness that is regulated by the spacers and the two sample surfaces of the plates and is equal to or less than 30 um with a small variation.