Loading patent…
AssigneeArizona Board of Regents on Behalf of the University of Arizona
InventorsJohn C. Jewett, Flora W. Kimani, Lindsay Guzman, Brandon M. Cornali
Estimating the term…
Triazabutadiene molecules as cleavable cross-linkers adapted to cross-link components with click chemistry, e.g., clickable triazabutadienes. For example, in some embodiments, the triazabutadienes feature alkyne handles attached to the imidazole portion or the aryl portion of the triazabutadienes, wherein the alkyne handles can link to azide handles (e.g., azide handles disposed on other components) via click chemistry. Also described are methods of producing said clickable triazabutadienes and methods of use of said clickable triazabutadienes. The present invention also features methods of cleaving said clickable triazabutadienes, e.g., for liberating the diazonium species for further chemical reactions.
A clickable triazabutadiene according to Formula C wherein both X1 and X2 comprise a terminal alkyne handle;
A clickable triazabutadiene according to Formula C wherein both X1 and X2 comprise a terminal alkyne handle;
A clickable triazabutadiene according to Formula C wherein both X1 and X2 comprise a terminal alkyne handle, wherein the alkyne handle of X1 is adapted to cross-link to an azide handle of a first linking component via click chemistry, and the alkyne handle of X2 is adapted to cross-link to an azide handle of a second component via click chemistry
Dependencies are inferred from the claim text.