# US 10,118,030 B2 · Omnidirectional deployable multichannel neural electrode system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,118,030 B2 - Document ID: US10118030B2 - Status: Granted - Kind: B2 - Application number: 14/519,346 - Filed: 2014-10-21 - Published: 2015-04-23 - Granted: 2018-11-06 - Earliest claimed: 2013-10-21 - Assignees: NeuroNexus Technologies, Inc. - Applicants: NeuroNexus Technologies, Inc. - Inventors: David S. Pellinen; Bencharong Suwarato; Rio J. Vetter; Jamille Farraye Hetke; Daryl R. Kipke - Web page: https://patentgrep.com/patent/US10118030B2 ## CPC - A61N 1/0558: {Anchoring or fixation means therefor} - A61B 5/293: Invasive - A61M 25/003: {characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves (catheter tips A61M25/0067)} - A61M 25/007: {Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked} - A61N 1/0534: {Electrodes for deep brain stimulation} - A61N 1/36017: {with leads or electrodes penetrating the skin} - G03F 7/40: Treatment after imagewise removal, e.g. baking - A61M 2025/0031: {characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - G03F: PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR; (phototypographic composing devices B41B; photosensitive materials or processes for photographic purposes G03C; electrophotography, sensitive layers or processes therefor G03G) ## Abstract A neural probe system having a single guide tube that is inserted into neural tissue and from which a number of neural probes can be deployed is described. Each probe is deployable into tissue along a desired trajectory. This is done by supporting the electrode array on a spring tape-type carrier that maintains axial stiffness once the neural probe has deployed out a channel in the guide tube. That way, a target neural tissue is bounded by an increased number of neural probes while minimizing trauma to surrounding body tissue. ## Claims ### Claim 1 A neural intervention system, comprising: a guide tube comprising a guide tube sidewall extending along a longitudinal axis from a proximal guide tube portion having a proximal guide tube end to a distal guide tube portion having a distal guide tube end, wherein a tube lumen extends from the proximal guide tube end to at least the distal guide tube end; a plurality of deployment channels disposed inside the guide tube, each of the plurality of deployment channels comprising a channel sidewall defining a channel lumen extending from a proximal channel open end to a distal channel open end as an open port at the guide tube sidewall, wherein the proximal channel open end of a first deployment channel of the plurality of deployment channels resides at a first location along a first imaginary plane aligned substantially perpendicular to the longitudinal axis and wherein the proximal channel open end of a second deployment channel of the plurality of deployment channels resides at a second location along the first imaginary plane radially closer to the longitudinal axis; an actuation mechanism having a length extending from a proximal actuation end to a distal actuation portion; and a plurality of neural probes that is registered with the plurality of deployment channels and that is connected to a manifold attached to the distal actuation portion of the actuation mechanism, at least one neural probe extending from a proximal probe end to a distal probe portion having a distal probe end, wherein the distal probe portion has at least one electrode configured for electrical stimulation of body tissue or recording of biological characteristics, and wherein at least the distal probe end is received in at least one deployment channel of the plurality of deployment channels; and wherein the proximal probe end is connected to the distal actuation portion, the proximal actuation end is movable in a distal direction along the longitudinal axis to cause the at least one neural probe to move through the at least one deployment channel and out the distal channel open end to thereby move the at least one electrode into a body tissue. ### Claim 2 (depends on 1) The neural intervention system of claim 1 wherein the proximal channel open end of one of the channel lumens of one of the plurality of deployment channels resides along the first imaginary plane to the distal channel open end substantially forms an angle ranging from 10 degrees to 180 degrees with respect to the longitudinal axis. ### Claim 3 (depends on 1) The neural intervention system of claim 1 wherein the distal guide tube end is either pointed or curved. ### Claim 4 (depends on 1) The neural intervention system of claim 1 wherein the plurality of deployment channels comprises at least two deployment channels, each of the at least two deployment channels having its proximal channel open end residing along the first imaginary plane, but with a first one of the at least two deployment channels having its distal channel open end as a first open port at a more distal location along the guide tube sidewall than the distal channel open end of the other of the at least two deployment channels. ### Claim 5 (depends on 1) The neural intervention system of claim 1 wherein the open port formed in the guide tube sidewall by the distal channel open end has a rectangular cross-section or a tape spring-type shaped cross-section. ### Claim 6 (depends on 1) The neural intervention system of claim 1 wherein the neural probe is configured to extend outwardly in a substantially radial direction upon deployment from the at least one deployment channel and out the distal channel open end thereof. ### Claim 7 (depends on 1) The neural intervention system of claim 1 wherein at least two of the plurality of neural probes have different lengths from one another. ### Claim 8 A neural intervention system, comprising: a guide tube extending along a longitudinal axis, wherein a tube lumen extends through a portion of the guide tube; a plurality of deployment channels disposed in a distal portion of the guide tube, each deployment channel extending from a proximal channel open end to a distal channel open end, wherein the distal channel open end has a trajectory that is off-axis with respect to the longitudinal axis, wherein the proximal channel open end of a first deployment channel of the plurality of deployment channels resides at a first location along an imaginary plane aligned substantially perpendicular to the longitudinal axis; and wherein the proximal channel open end of a second deployment channel of the plurality of deployment channels resides at a second location along the imaginary plane that is radially closer to the longitudinal axis; a plurality of neural probes extending from a plunger, each of the neural probes having at least one electrode configured for electrical stimulation of body tissue or recording of biological characteristics, wherein a first subset of the plurality of neural probes is coupled to a first manifold and a second subset of the plurality of neural probes is coupled to a second manifold; and an actuation mechanism having a length extending from a proximal actuation end to the plunger, the actuation mechanism being is movable to cause a first neural probe of the plurality of neural probes to move through a corresponding deployment channel to insert the first neural probe into body tissue. ### Claim 9 (depends on 8) The neural intervention system of claim 8 wherein the proximal channel open end of the each of the plurality of deployment channels is disposed on a common imaginary plane. ### Claim 10 (depends on 8) The neural intervention system of claim 8 wherein the trajectory is determined by an angle with respect to the longitudinal axis and a rotational position around the longitudinal axis. ### Claim 11 (depends on 10) The neural intervention system of claim 10 wherein the angle is in a range from about 10 degrees to about 180 degrees with respect to the longitudinal axis. ### Claim 12 (depends on 8) The neural intervention system of claim 8 wherein the actuation mechanism is moveable along the longitudinal axis of the guide tube. ### Claim 13 (depends on 8) The neural intervention system of claim 8 wherein the distal channel open end of a first deployment channel of the plurality of deployment channels is disposed at a more distal location along the guide tube the distal channel open end of a second deployment channel of the plurality of deployment channels. ### Claim 14 (depends on 8) The neural intervention system of claim 8 wherein the distal channel open ends have a rectangular cross-section or a curved cross-section. ### Claim 15 (depends on 8) The neural intervention system of claim 8 wherein the plurality of neural probes includes at least two neural probes having different lengths from one another. ### Claim 16 (depends on 8) The neural intervention system of claim 8, wherein the first and second manifolds are configured to support the first and second subsets of the plurality of neural probes in concentric circles. ### Claim 17 A neural intervention system, comprising: a guide tube extending along a longitudinal axis, wherein a tube lumen extends through a portion of the guide tube; a plurality of deployment channels disposed in a distal portion of the guide tube, each deployment channel extending from a proximal channel open end to a distal channel open end, wherein the distal channel open end has a trajectory that is off-axis with respect to the longitudinal axis; a plurality of neural probes extending from a plunger, each of the neural probes having at least one electrode configured for electrical stimulation of body tissue or recording of biological characteristics, wherein a first subset of the plurality of neural probes is coupled to a first manifold and a second subset of the plurality of neural probes is coupled to a second manifold; and wherein the first and second manifolds are configured to support the first and second subsets of the plurality of neural probes in concentric circles; and an actuation mechanism having a length extending from a proximal actuation end to the plunger, the actuation mechanism being is movable to cause a first neural probe of the plurality of neural probes to move through a corresponding deployment channel to insert the first neural probe into body tissue. ### Claim 18 (depends on 17) The neural intervention system of claim 17 wherein the proximal channel open end of a first deployment channel of the plurality of deployment channels resides at a first location along a first imaginary plane aligned substantially perpendicular to the longitudinal axis. ### Claim 19 (depends on 18) The neural intervention system of claim 18 wherein the proximal channel open end of a second deployment channel of the plurality of deployment channels resides at a second location along the first imaginary plane that is radially closer to the longitudinal axis. ### Claim 20 (depends on 17) The neural intervention system of claim 17 wherein a distal guide tube end of the guide tube is either pointed or curved.