# US 10,117,965 B1 · Intraocular lens material

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- Number: US 10,117,965 B1
- Document ID: US10117965B1
- Status: Granted
- Kind: B1
- Application number: 15/772,273
- Filed: 2017-07-27
- Published: 2018-11-08
- Granted: 2018-11-06
- Earliest claimed: 2016-07-28
- Assignees: Menicon Co., Ltd.
- Applicants: Menicon Co., Ltd
- Inventors: Yuya Suganuma; Hiroko Nomura; Tatsuya Ojio
- Web page: https://patentgrep.com/patent/US10117965B1

## CPC

- A61L 27/16: obtained by reactions only involving carbon-to-carbon unsaturated bonds
- A61L 27/50: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials}
- C08F 220/30: containing aromatic rings in the alcohol moiety
- G02B 1/041: {Lenses}
- G02B 1/043: {Contact lenses}
- A61L 2430/16: for reconstruction of eye parts, e.g. intraocular lens, cornea
- C08F 220/286: {and containing polyethylene oxide in the alcohol moiety, e.g. methoxy polyethylene glycol (meth)acrylate}
- C08F 220/301: {and one oxygen in the alcohol moiety}
- C08F 222/145: {the ester chains containing seven or more carbon atoms}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- C08F: MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS

## Abstract

An intraocular lens material disclosed in the present description includes an aromatic ring-containing acrylate structural unit, an alkoxyalkyl methacrylate structural unit including an alkoxy group having 4 or less carbon atoms, a hydrophilic structural unit based on a hydrophilic monomer, and a cross-linking structural unit based on a cross-linkable monomer.

## Claims

### Claim 1

An intraocular lens material comprising:
an aromatic ring-containing acrylate structural unit;
an alkoxyalkyl methacrylate structural unit including an alkoxyalkyl group having 4 or less carbon atoms;
an alkyl acrylate structural unit including an alkyl group having 1 to 20 carbon atoms,
a hydrophilic structural unit based on a hydrophilic monomer;
a cross-linking structural unit based on a cross-linkable monomer,
wherein the aromatic ring-containing acrylate structural unit is phenoxyethyl acrylate structural unit,
the alkoxyalkyl methacrylate structural unit is an ethoxyethyl methacrylate structural unit,
the alkyl acrylate structural unit is an ethyl acrylate structural unit, and
a base material consists of the aromatic ring-containing acrylate structural unit, the alkoxyalkyl methacrylate structural unit and the alkyl acrylate structural unit, and the base material include one kind of the aromatic ring-containing monomer.

### Claim 2 (depends on 1)

The intraocular lens material according to claim 1, wherein the alkoxyalkyl methacrylate structural unit is included in an amount within the range of from 10 parts by mass to 70 parts by mass inclusive based on 100 parts by mass of the total amount of the base material.

### Claim 3 (depends on 1)

The intraocular lens material according to claim 1, wherein the alkoxyalkyl methacrylate structural unit is included in an amount within the range of from 10 parts by mass to 40 parts by mass inclusive based on 100 parts by mass of the total amount of the base material.

### Claim 4 (depends on 1)

The intraocular lens material according to claim 1, wherein the hydrophilic structural unit is included in an amount within the range of from 15 parts by mass to 35 parts by mass inclusive by the outside ratio based on 100 parts by mass of the total amount of the base material.

### Claim 5 (depends on 1)

The intraocular lens material according to claim 1, wherein the cross-linking structural unit is included in an amount within the range of from 2 parts by mass to 4 parts by mass inclusive by the outside ratio based on 100 parts by mass of the total amount of the base material.

### Claim 6 (depends on 1)

The intraocular lens material according to claim 1, wherein the alkyl acrylate structural unit is included in an amount within the range of from 10 parts by mass to 35 parts by mass inclusive based on 100 parts by mass of the total amount of the base material.

### Claim 7 (depends on 1)

The intraocular lens material according to claim 1, wherein the aromatic ring-containing acrylate structural unit is included in an amount within the range of from 15 parts by mass to 80 parts by mass inclusive based on 100 parts by mass of the total amount of the base material.

### Claim 8 (depends on 1)

The intraocular lens material according to claim 1, wherein the hydrophilic structural unit is a hydroxyethyl methacrylate structural unit.

### Claim 9 (depends on 1)

The intraocular lens material according to claim 1, wherein the cross-linking structural unit is a butanediol diacrylate structural unit.

### Claim 10 (depends on 1)

The intraocular lens material according to claim 1, wherein the aromatic ring-containing acrylate structural unit is included in an amount within the range of from 30 parts by mass to 80 parts by mass inclusive based on 100 parts by mass of the total amount of the base material,
the alkoxyalkyl methacrylate structural unit is included in an amount within the range of from 10 parts by mass to 40 parts by mass inclusive based on 100 parts by mass of the total amount of the base material,
the alkyl acrylate structural unit is included in an amount within the range of from 10 parts by mass to 35 parts by mass inclusive based on 100 parts by mass of the total amount of the base material.
