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US 10,117,892 B2Granted
Devices and methods for reducing the appearance of cellulite
AssigneeAllergan, Inc.
InventorsTracy Ann Perry, Rui Avelar, Justin Schwab, Zachary Dominguez, Edwin Kayda
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Abstract
Methods and devices for use in reducing the appearance of dimpled skin or other undesirable appearance of skin in a cellulitic region of a patient are provided. The methods include the steps of disrupting fibrous septae located beneath the skin of a cellulitic region and introducing a composition beneath the skin, the composition being effective to reduce or prevent regrowth of the fibrous septae.
Claims9
A composition useful for reducing the appearance of dimpled skin or other undesirable appearance of skin in a cellulitic region of a patient, the composition comprising:
- an injectable gel comprising:
- a mixture of at least collagenase I and collagenase II in a mass ratio of 1:1, the mixture having a specific activity of at least about 500 SRC units/mg;
- and
- at least one hyaluronic acid combined with or mixed with the collagenase I and collagenase II, the at least one hyaluronic acid present in an amount effective to provide a physical barrier between tissue planes to discourage regrowth of septal bands disrupted by the collagenase mixture:
- and
- at least one lipolytic agent capable of causing a reduction in the fat stores of adipocytes, wherein the at least one lipolytic agent is selected from the group consisting of phosphatidylcholine, conjugated linoleic acid, deoxycholate, magnolol, and a lipolytic enzyme.
3 more elements
Dependencies are inferred from the claim text.