# US 10,117,891 B2 · Cannabinoid composition for treating pain

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- Number: US 10,117,891 B2
- Document ID: US10117891B2
- Status: Granted
- Kind: B2
- Application number: 15/104,554
- Filed: 2015-09-16
- Published: 2017-02-02
- Granted: 2018-11-06
- Earliest claimed: 2014-09-16
- Assignees: India Globalization Capital, Inc.
- Applicants: India Globalization Capital, Inc.
- Inventors: Ramachandra Mukunda; Ranga Chelva Krishna
- Web page: https://patentgrep.com/patent/US10117891B2

## CPC

- A61K 31/714: Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol}
- A61K 36/3482: {Cannabis}
- A61K 47/44: Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin (synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14)
- A61P 19/02: for joint disorders, e.g. arthritis, arthrosis
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 25/02: for peripheral neuropathies
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A combination of THC, CBD and Cobalamin (in a ratio of about 63%, 27% and 10%, respectively) is used with a topical carrier such as Shea butter cream to relieve pain. The THC and CBD mixture is extracted from a Cannabis Indica dominant strain using high pressure and carbon dioxide (CO2) as a solvent and comprises: Tetrahydrocannabinol “THC” (9-Tetrahydrocannabinol (delta-9 THC), 8-Tetrahydrocannabinol (Delta-8 THC) and 9-THC Acid), Cannabidiol “CBD”, Cannabinol “CBN”, Cannabichromene (“CBC”), Cannabigerol (“CBG”), terpenoids and flavonoids. The Shea butter is an extract from the Shea nut from the Shea tree (Vitellaria paradoxa).

## Claims

### Claim 1

A topical composition for treating pain consisting essentially of: (i) tetrahydrocannabinol (THC) in an amount from about 50% to about 70% by weight; (ii) cannabidiol (CBD) in an amount from about 20% to about 40% by weight; (iii) cobalamin in an amount from about 5% to about 20% by weight and (iv) a carrier wherein the percentage amounts of THC, CBD and cobalamin is based on the total weight of THC, CBD and cobalamin in the composition.

### Claim 2 (depends on 1)

Composition of claim 1 wherein THC is used in an amount greater than CBD and cobalamin is used in an amount less that either of THC or CBD.

### Claim 3 (depends on 2)

Composition of claim 2 wherein THC is used in an amount greater the 50% by weight, CBD in an amount up to about 30% by weight and cobalamin in an amount up to about 20% by weight.

### Claim 4 (depends on 3)

Composition of claim 3 wherein THC is used in an amount of about 63% by weight, CBD in an amount of about 27% and cobalamin in an amount of about −11%.

### Claim 5 (depends on 1)

Composition of claim 1 wherein THC and CBD are extracted from Cannabis Sativa.

### Claim 6 (depends on 1)

Composition of claim 1 wherein THC and CBD are synthetic.

### Claim 7 (depends on 1)

Composition of claim 1 wherein CBD is organic CBD also containing cannabinol (CBN), cannabichromene (CBC), cannabigerol (CBG), terpenoids and flavonoids.