# US 10,117,841 B2 · Volatile organic compound formulations having antimicrobial activity > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,117,841 B2 - Document ID: US10117841B2 - Status: Granted - Kind: B2 - Application number: 14/322,757 - Filed: 2014-07-02 - Published: 2016-09-01 - Granted: 2018-11-06 - Earliest claimed: 2013-07-02 - Assignees: Ecoplanet Environmental LLC - Applicants: Ecoplanet Environmental LLC - Inventors: Gary A. Strobel; Bryan Blatt - Web page: https://patentgrep.com/patent/US10117841B2 ## CPC - A61K 31/19: Carboxylic acids, e.g. valproic acid (salicylic acid A61K31/60) - A01N 37/02: Saturated carboxylic acids or thio analogues thereof; Derivatives thereof - A01N 37/12: containing the group [IMAGE cpc-sch-A01N-0932.gif], wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof - A61K 31/22: of acyclic acids, e.g. pravastatin - A61K 36/062: Ascomycota - A61K 47/44: Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin (synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14) - A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs - Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS - A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION - Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE ## Abstract The present invention includes novel chemical formulations having antimicrobial activity and their methods of use thereof. In some embodiments, the formulation further comprises at least one fungus. ## Claims ### Claim 1 A formulation having antimicrobial activity and comprising an antimicrobial component consisting of (i) at least one acid selected from the group consisting of propanoic acid and isobutyric acid; and (ii) an effective amount of isoamyl hexanoates; and wherein said antimicrobial component is the only antimicrobial agent in the formulation. ### Claim 2 (depends on 1) The formulation of claim 1 further comprising at least one amino acid and at least one salt. ### Claim 3 (depends on 1) The formulation of claim 1, wherein the at least one acid is propanoic acid and isobutyric acid combined at a ratio of about 1:1 by volume. ### Claim 4 A formulation having antimicrobial activity and comprising (1) an antimicrobial component consisting of (i) at least one acid selected from the group consisting of propanoic acid and isobutyric acid; and (ii) an effective amount of isoamyl hexanoates; and (2) at least one component selected from the group consisting of an amino acid, glucose, sodium chloride, potassium chloride, and magnesium acetate; and wherein said antimicrobial component is the only antimicrobial agent in the formulation. ### Claim 5 (depends on 4) The chemical formulation of claim 4, wherein the at least one acid is propanoic acid and isobutyric acid. ### Claim 6 (depends on 5) The formulation of claim 5, wherein the at least one component is an amino acid and a salt selected from the group consisting of sodium chloride, potassium chloride, and a mixture thereof. ### Claim 7 (depends on 5) The formulation of claim 5, wherein the propanoic acid and isobutyric acid are combined at a ratio of about 1:1 by volume. ### Claim 8 An antimicrobial component for use directly or as a part of an antimicrobial formulation having antimicrobial activity and consisting of (i) at least one acid selected from the group consisting of propanoic acid and isobutyric acid; (ii) an effective amount of isoamyl hexanoates; and (iii) a pharmaceutically acceptable carrier. ### Claim 9 (depends on 8) The antimicrobial component of claim 8, wherein the at least one acid is a combination of propanoic acid and isobutyric acid. ### Claim 10 (depends on 8) The antimicrobial component of claim 8, wherein the at least one acid is propanoic acid. ### Claim 11 (depends on 9) The antimicrobial component of claim 9, wherein the propanoic acid and isobutyric acid are combined at a ratio of about 1:1 by volume. ### Claim 12 (depends on 8) A method of treating a human or animal having a disease or disorder associated with a microbial infection, comprising administering to the human or animal an effective amount of the antimicrobial component of claim 8. ### Claim 13 (depends on 12) The method of claim 12, wherein the microbial infection is caused by Escherichia coli, Staphylococcus aureus, or Salmonella. ### Claim 14 An antimicrobial component for use directly or as part of an antimicrobial formulation having antimicrobial activity and consisting of a combination of (i) at least one acid selected from the group consisting of propanoic acid and isobutyric acid; and (ii) an effective amount of isoamyl hexanoates. ### Claim 15 (depends on 14) The antimicrobial component of claim 14, wherein the at least one acid in the combination is propanoic acid. ### Claim 16 (depends on 14) The antimicrobial component of claim 14, wherein the at least one acid in the combination is propanoic acid and isobutyric acid. ### Claim 17 (depends on 14) The antimicrobial component of claim 14, wherein the at least one acid in the combination is propanoic acid and isobutyric acid combined at a ratio of about 1:1 by volume. ### Claim 18 (depends on 14) A method of treating a human or an animal having a disease or disorder associated with a microbial infection, comprising administering to the human or animal an effective amount of the chemical antimicrobial component of claim 14. ### Claim 19 (depends on 18) The method of claim 18, wherein the microbial infection is caused by Escherichia coli, Staphylococcus aureus, or Salmonella.