# US 10,117,586 B1 · Continuous non-invasive wearable blood pressure monitoring system

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- Number: US 10,117,586 B1
- Document ID: US10117586B1
- Status: Granted
- Kind: B1
- Application number: 14/675,639
- Filed: 2015-03-31
- Granted: 2018-11-06
- Earliest claimed: 2014-03-31
- Assignees: Sensogram Technologies, Inc.
- Applicants: Sensogram Technologies, Inc.
- Inventors: Vahram Mouradian; Armen Poghosyan
- Web page: https://patentgrep.com/patent/US10117586B1

## CPC

- A61B 5/02108: {from analysis of pulse wave characteristics}
- A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)}
- A61B 5/02416: {using photoplethysmograph signals, e.g. generated by infrared radiation (A61B5/14552 takes precedence)}
- A61B 5/0082: {adapted for particular medical purposes}
- A61B 2560/0223: of calibration, e.g. protocols for calibrating sensors
- A61B 2560/0475: Special features of memory means, e.g. removable memory cards
- A61B 2562/0238: Optical sensor arrangements for performing transmission measurements on body tissue
- A61B 2576/00: Medical imaging apparatus involving image processing or analysis (A61B1/00009, A61B6/52 and A61B8/52 take precedence)
- G16H 30/40: for processing medical images, e.g. editing
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

Presented are embodiments of an apparatus and methodology integrated in the system for non-invasive, continuous, wearable, remote and mobile monitoring of human blood pressure by photoplethysmography (PPG) based sensor and an electronic processing unit with the embedded radio allowing the reading and transmittal of the read blood pressure data to the remote location.

## Claims

### Claim 1

A method of continuously monitoring blood pressure, the method comprising:
(a) performing a calibration sub-process to determine and store inductance (L) and compliance of the cardiovascular system (C) for each individual user;
(b) retrieving the stored values for L and C;
(c) receiving a photoplethysmographic (PPG) signal for each pulse or for a given time period;
(d) filtering the received PPG signal to produce a clean PPG signal;
(e) determining the heart rate;
(f) determining the peripheral resistance using the heart rate;
(g) calculating the blood pressure using the clean PPG signal, the peripheral resistance, L and C; and
(h) determining the systolic and diastolic blood pressure.

### Claim 2 (depends on 1)

The method of claim 1, further comprising repeating steps (b) through (h) for each predetermined time period.

### Claim 3 (depends on 1)

The method of claim 1, further comprising repeating steps (b) through (h) for each pulse of a user.

### Claim 4 (depends on 1)

The method of claim 1, further comprising storing the systolic and diastolic blood pressure in a memory.

### Claim 5

A system for continuously monitoring blood pressure, the system comprising:
a light source;
an optical sensor positioned to receive reflected light from the light source;
a signal processing unit adapted to receive an electrical signal from the optical sensor and configured to output a clean digital signal;
a microprocessor in communication with the light source, the signal processing unit, a memory and a computer/wireless interface, the microprocessor having instructions for:
(a) performing a calibration sub-process to determine and store inductance (L) and compliance of the cardiovascular system (C) for each individual user;
(b) retrieving the stored values for L and C;
(c) receiving a photoplethysmographic (PPG) signal for each pulse or for a given time period;
(d) filtering the received PPG signal to produce a clean PPG signal;
(e) determining the heart rate;
(f) determining the peripheral resistance using the heart rate;
(g) calculating the blood pressure using the clean PPG signal, the peripheral resistance, L and C; and
(h) determining the systolic and diastolic blood pressure.

### Claim 6 (depends on 5)

The method of claim 5, further comprising repeating instructions (b) through (h) for each predetermined time period.

### Claim 7 (depends on 5)

The method of claim 5, further comprising repeating instructions (b) through (h) for each pulse of a user.